Dosage ; Angina pectoris and hypertension; 30-60mg TID or QID
(max 480g). For long acting formulations:
Hypertension and angina; 90-120mg BD (up to 360mg daily)
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Diltiazem | Arrow Generics | Metro Pharmaceuticals Ltd. | 60mg | 84 | Tablet | per tablet | KES 560 |
| Mono-Tildiem | Sanofi Aventis | Surgipharm Ltd | 200mg | 28 | Tablet | per tablet | KES 2,076 |
| Mono-Tildiem | Sanofi Aventis | Surgipharm Ltd | 300mg | 28 | Tablet | per tablet | KES 2,058 |
| Mono-Tildiem | Sanofi Aventis | Surgipharm Ltd | 60mg | 30 | Tablet | per tablet | KES 831 |
| Tildiem | Sanofi Aventis | Surgipharm Ltd | 60mg | 30 | Tablet | per tablet | KES 831.00 |
| Calzem | Efroze Chemical Industries Ltd | Njimia Pharmaceuticals Ltd. | 1% | 180ml | Mouthwash | KES POR | |
| Calzem SR | Efroze Chemical Industries Ltd | Njimia Pharmaceuticals Ltd. | 60mg | 20 | Tablet | per tablet | KES 311.00 |
| Diltiazem SR | Arrow Generics | Metro Pharmaceuticals Ltd (Uganda) | 60mg | 84 | Tablet | per tablet | KES 560.00 |
| Diltigesic | Troikaa Pharmaceuticals | Harley's Limited | 2% | 30gm | gel | KES 700.00 | |
| Mono-Tildiem | Sanofi Aventis | Laborex Kenya Eurapharma Ltd | 300mg | 28 | Capsule | per capsule | KES 2,750.00 |
|
Diltiazem More info |
|
|---|---|
| Mode Of Action | Calcium channel blocker |
| Drug Indication | Hypertension, prophylaxis and treatment of angina |
| Precautions | Pregnancy, Wolff-Parkinson-White Syndrome, cardiomyopathy, attenuated neuromuscular transmission, first degree AV block, patients on beta-blockers, acute phase of myocardial infarction, children. |
| Contra-Indications | Sick sinus syndrome, heart failure, AV and SA block, disopyramide within 48hours, hypotension associated with cardiogenic shock, acute stage of myocardial infarction, bradycardia, porphyria. |
| Side Effects | GI disturbances, flushing, fatigue, dizziness, headache, ankle oedema.Others: gynaecomastia, gingival hyperplasia, and hypersensitivity reactions. |
| Dosage | Angina pectoris and hypertension; 30-60mg TID or QID (max 480g). For long acting formulations: Hypertension and angina; 90-120mg BD (up to 360mg daily). |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTI NG ON THE CARDIO-VASCULAR SYSTEM |
| Drug Sub-Category | Calcium-channel blockers |